Endocrine Abstracts

Introduction: Perivascular adipose tissue has been implicated in vascular physiology and pathology, including atherosclerosis. Local adipokine production is one of the paracrine mechanisms involved in this adipose tissue fuction. We investigated the expression of adipokines chemerin and adiponectin and their receptors CMKLR1 and T-cadherin, respectively, in human coronary arterial wall and pericoronary fat as well as their correlation with coronary atherosclerosis.<p class...

Introduction: Periadventitial adipose tissue has been implicated in vascular physiology and pathology, including atherosclerosis, through paracrine and endocrine mechanisms, mainly adipokine production. We investigated the expression of adipokines chemerin and adiponectin and their receptors CMKLR1 and T-cadherin, respectively, in human aortic arterial wall and periaortic fat as well as their correlation with aortic atherosclerosis.Methods: Paraffin embe...

Introduction: Adipose tissue is a source of peptides with paracrine and endocrine actions, called adipokines. Adipokines produced by periadventitial fat have been implicated in vascular pathology, including atherosclerosis. We investigated the expression of novel adipokines chemerin and vaspin, as well as visfatin, apelin and adiponectin in human pericoronary and periaortic fat in correlation with coronary and aortic atherosclerosis.Methods: Paraffin emb...